Synthesis of (¡Ý)-ent-Altholactone, (¡Ü)-7a-epi-Altholactone, (¡Ý)-ent-Isoaltholactone and (¡Ý)-7a-epi-Isoaltholactone from 2,3-O-Cyclohexylidene-D-glyceraldehyde£±
Akira HIRATATE, Hiromasa KIYOTA and Takayuki ORITANI
J. Pestic. Sci.
26, 361-365 (2001)
Synthesis of the diastereomers of (¡Ü)-altholactone, an antitumor acetogenin from various Goniothalamus species, was achieved. Four isomers including 3a,7a-trans-fused analogs were synthesized from 2,3-O-cyclohexylidene-D-glyceraldehyde via twice separation of diastereomers.
