Development of a Simulation Model "InPest" for Prediction of Indoor Behaviors of House-hold Insecticides
A computer software (to be registered as InPest) was developed in order to make a risk assessment of indoor-use insecticides to both applicators and indoor occupants in various applications including space spraying, electric vaporizing, broadcast spraying and residual spraying. The movement of an insecticide in a sprayed room was described as precisely as possible by utilizing various physicochemical equations, which were incorporated in the Fugacity model (Level IV). When insecticide information regarding molecular weight, vapor pressure, water solubility and octanol/water partition coefficient is available, InPest is able to simulate the time-dependent concentrations of the insecticide in the air and residual amounts on floor, wall and ceiling compartments under various conditions. Simulation data indicate that the predicted behavior of the insecticide fully agrees with the measured one. Based on the predicted concentrations, the levels of exposure to applicators and room occupants via inhalation, dermal or oral intake can be computed and compared with the mammalian toxicological data. Thus, InPest is a powerful tool for evaluating the safety of indoor-use insecticides with regard to human health. |