Synthesis and Fungicidal Activities of 3-(a-Alkoxyiminobenzyl)isoxazole Derivatives
Hiroyuki KAI, Tsuneo ICHIBA, Minoru TOMIDA and Michio MASUKO
J. Pestic. Sci.
24, 149-155 (1999)
A series of 3-(a-alkoxyiminobenzyl)isoxazole derivatives were synthesized and their fungicidal activities against crop diseases were assessed. Studies of the structure-activity relationships revealed the strongest fungicidal activity when the alkoxyimino moiety was substituted with a methyl group. When the position-2 of the benzene ring on the benzyl moiety was substituted with a phenoxymethyl group, a good fungicidal activity was obtained. Among the compounds examined, 3-[2-(2,5-dimethylphenoxymethyl)-a-methoxyiminobenzyl]isoxazole showed potent fungicidal activity against cucumber powdery mildew, wheat powdery mildew and wheat eye spot.
